Treatments

OPAT (outpatient parenteral antimicrobial therapy)

SERVICE(S):

Some infections require long-term treatment to fight the bacteria. This treatment can sometimes be continued safely at home once it has been started up at the hospital. This will enable you to resume your daily activities more quickly, in your familiar surroundings.

What is OPAT?

OPAT stands for Outpatient Parenteral Antimicrobial Therapy.

  • Outpatient: The treatment does not take place in the hospital.
  • Parenteral: The antibiotic is administered intravenously (into a blood vessel) or intramuscularly (into the muscles).

Sometimes intravenous antibiotics are more effective than oral antibiotics, or no oral alternative is available.

  • Antimicrobial: The antibiotic is active against microorganisms that can cause (serious) infections.

The main goal of OPAT is to complete the treatment safely and effectively in the comfort of your own home. This allows you to quickly resume your daily activities.

You must give your prior consent as a patient or guardian (consent form).

Remote Care

OPAT treatment is part of “remote care”: you can recover at home and do not need to stay unnecessarily long in the hospital.

Your health is closely monitored using smart technology, while you recover in your own familiar environment.

Practical questions about OPAT

  • Where can I get my antibiotics?

    The antibiotics are available through the hospital pharmacy.

  • Where can I get the materials?

    Part of the materials is provided by the home nurse (syringes, needles, etc.). The rest is supplied by the hospital.

    One week after your admission, you will have a consultation with the infectious disease specialist. After that, a consultation takes place every two weeks.

    During each consultation, new materials are provided for a maximum of two weeks. In case of early discontinuation, the hospital will not take back the materials.

  • Who administers the antibiotics?

    The antibiotics are administered by a home nurse via a catheter.

    There are different types of catheters:

    • Port-A-Cath: a port catheter implanted under the skin.
    • PICC/Midline: a catheter inserted through a vein in the arm.
    • Central catheter

    The type of catheter you receive depends on several factors, such as the quality of the veins and the expected duration of the antibiotic treatment.

  • Is OPAT safe?

    OPAT is a safe way to continue your treatment at home.

    The first doses are given in the hospital so that doctors and nurses can monitor how your body reacts to the medication. Any medication can cause an allergic reaction.

    If you experience skin rash, swelling of the face, or breathing difficulties at home, immediately notify your general practitioner or home nurse.

  • How long does an OPAT treatment last?

    The duration of the treatment depends on the nature of the infection. You can ask your doctor for more information about this.

  • How much does an OPAT treatment cost?

    Most antibiotics are partially or fully reimbursed by the RIZIV (NIHDI). For this, the advising physician of your health insurance fund must first give approval.

    You pay a contribution for the other medical materials.

    You may also be entitled to additional reimbursement through your hospitalization insurance. Our social service will visit you during your admission to discuss this.

OPAT in Y-mail

Dr. Wim Terryn gave an interview about OPAT in Y-Mail, the hospital magazine of Jan Yperman Hospital. Consult the article here.

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E-learning on OPAT by the Department of Care

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Last modified on 10 June 2026

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