Disease

Cushing's disease

This is a rare disorder in which the adrenal glands produce excess hormones. The cause lies in the pituitary gland (pituitary tumour).

Symptoms are often vague and usually develop slowly:

  • fatigue
  • developing a full face and fat accumulation in the abdomen
  • muscle weakness when standing up
  • developing brittle skin, bruising and skin discolouration.

Note that these symptoms can also be caused by taking cortisone (e.g. Medrol/prednisolone for lung disease, rheumatism, chemotherapy) or for diseases other than adrenal pathology.

If you suspect this, please contact your GP. Bring the results of any examinations with you to the endocrinology consultation. You are not required to fast. An additional blood test, 24-hour urine collection and dexamethasone suppression test (in the context of confirming the abnormality) and/or other tests (to determine the cause of excessive cortisol production) may also be performed, e.g. a pituitary NMR. After the diagnosis, we will determine the further policy together with you and the other doctors (including neurologist, ophthalmologist, GP and possibly neurosurgeon).

Treatments

Your doctor will discuss the treatment options with you.

Last modified on 6 July 2022

Speciality

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